Seattle
  • Current Conditions
    50°
    Cloudy
  • 1:00pm
    51°
  • 4:00pm
    50°
Full Forecast »
Severe Weather Alert
Affected Counties

Researchers Identify Another Cancer Gene

Genetic Testing May Prove Life-Saving

UPDATED: 7:03 am PDT August 29, 2003

Scientists now believe that about one in five cancers is at least partly inherited.

Kathy Lambert On Thursday, Chicago researchers confirmed the discovery of another cancer gene that may be the most deadly yet. The hope is that the discovery will lead to earlier diagnosis, treatment, or prevention -- like what's currently being offered to women with a breast cancer gene.

It was a yearly mammogram that discovered a tiny tumor in Kathy Lambert's left breast. In a way, she'd been expecting it.

"My mother had cancer and died at 54," said Lambert (pictured, right). "And then her mother had it, and then my mom had a cousin who died at 50. So, we've always wondered when it's going to be my time to have it."

BREAST CANCER
FROM OUR PARTNERS
Lambert's tumor was removed in its most curable stage. But at Northwestern Memorial Hospital in Chicago, genetics counselor Taya Young warned Lambert that her risk for more tumors remained high. She had inherited a BRCA gene for breast and ovarian cancer.

Young said that patients with BRCA I and II have up to an 87 percent risk of developing breast cancer, and up to a 44 percent risk of developing ovarian cancer.

Meanwhile, other researchers at Northwestern were confirming the existence of yet another cancer gene that's far more common -- it's in every 10th person.

"This gene is called TGEFBR1*6A. Just to shorten it, we call it 6A," said Dr. Virginia Kaklamani.

A cancer specialist, Kaklamani said the 6A mutation increases the risk of breast cancer by 48 percent, of ovarian cancer by 53 percent, and of colon cancer by 38 percent for women and men.

"In the U.S. in 2003, this gene should be responsible for more than 20,000 new cases of cancer," Kaklamani said.

But knowing about the gene now may save lives. It can lead to a new blood test for the mutation that will give patients the same early warning and the same chance to survive that Lambert had.

"There are things that we can do to reduce that risk and to make it so that they're living with a cancer risk, not dying from a cancer," Young said.

The research by Kaklamani's team is published in the Sept. 1 issue of the Journal of Clinical Oncology.


News Images & Video

kirotv.com Video

An employee of a Tracy, Calif., gym shares his experience after a nearly naked teenage boy shows at his work with a shackle padlocked around his ankle. More Details


Police Release 'Toys R Us' Shooting 911 Call
CNN Image
Police in Palm Desert, Calif., release the 911 call from a double-shooting Friday in a local "Toys R' Us" store. More Details



Shop At The Online Mall

Sponsor Links

Links We Like
Sponsored Content
Besieged by nagging aches and pains? You might have fibromyalgia. Read about the signs and symptoms. More Details

So you want a cool job huh? Find out what you could be making to do something you love. More Details

Paying down your debt is one of the most important things to do to get through a recession. Find out how you can lower your interest and escape your credit card debt. More Details

Learn about 7 of the most common skin rashes and everything you need to know to avoid getting them and treating them if you already do. More Details

Don’t be left out. Make the switch to Digital TV.

Health Topics & Information

An alarming number of people live with pain. Whether yours is chronic or acute, we can help you make it stop. Get pain management tips here! More Details

Revolution Health

Caregiving

What If Chemotherapy Doesn't Work?
Caring.com
Get The Facts On Chemotherapy Treatment And Side Effects. More Details



Caring.com

Diet & Fitness Tools

SparkPeople
Get in the competitive spirit and lose weight! SparkPeople is challenging cities across America to get fit and we want Seattle to lead the charge! Go to SparkSeattle.com make it happen! Join Now.
SparkPeople
E-Mail News Alerts
Get breaking news and daily headlines.
Browse all e-mail newsletters
Back To Top