Seattle
  • Current Conditions
    50°
    Drizzle
  • 1:00pm
    51°
  • 4:00pm
    50°
Full Forecast »
Severe Weather Alert
Affected Counties

New Drug Tested For Alzheimer's Disease

POSTED: 3:21 pm PDT April 6, 2005
UPDATED: 3:25 pm PDT April 6, 2005

Alzheimer's Disease robs patients of their memories.

Current therapies only slow down the disease, but a new drug in development would not only treat the symptoms; it may actually correct the problem.

Married for 59 years, Blanche Wiedenbaum remembers exactly how she met her husband Sy.

"We lived on the same block, and he used to watch me from his window across the street," she said.

But her memory is failing. She's in the early stages of Alzheimer's Disease.

"When she's out of the house with other people, they don't know she's got a problem. I think most of them don't realize it," Sy Wiedenbaum said.

She takes the medicine Aricept, one of the drugs proven to slow the disease, but she's also in a clinical trial with a new drug called Xaliproden.

In Alzheimer's Disease, clumps of an abnormal protein called amyloid build up in the brain cells, and cause them to degenerate and die.

Xaliproden prevents that buildup, and may even encourage new brain cells to grow.

"By blocking the deposition of amyloid within the neurons, and preventing the development of so-called plaques and tangles, we can hopefully keep the patients brain healthy," said Dr. Richard Singer, a Neurologist.

Singer is studying the drug. He says though it is not a cure, it does hold a lot of promise.

"So it's felt by doing this it will prevent not only the worsening of Alzheimer's but it will prevent the development and progression of it as we go along," Singer said.

As part of the experiment blanche doesn't know if she is getting the real drug or a placebo.

Either way, Sy hopes his wife will be able to hold onto her memories.

News Images & Video

kirotv.com Video

An employee of a Tracy, Calif., gym shares his experience after a nearly naked teenage boy shows at his work with a shackle padlocked around his ankle. More Details


Police Release 'Toys R Us' Shooting 911 Call
CNN Image
Police in Palm Desert, Calif., release the 911 call from a double-shooting Friday in a local "Toys R' Us" store. More Details



Shop At The Online Mall

Sponsor Links

Links We Like
Sponsored Content
Besieged by nagging aches and pains? You might have fibromyalgia. Read about the signs and symptoms. More Details

So you want a cool job huh? Find out what you could be making to do something you love. More Details

Paying down your debt is one of the most important things to do to get through a recession. Find out how you can lower your interest and escape your credit card debt. More Details

Learn about 7 of the most common skin rashes and everything you need to know to avoid getting them and treating them if you already do. More Details

Don’t be left out. Make the switch to Digital TV.

Health Topics & Information

An alarming number of people live with pain. Whether yours is chronic or acute, we can help you make it stop. Get pain management tips here! More Details

Revolution Health

Caregiving

What If Chemotherapy Doesn't Work?
Caring.com
Get The Facts On Chemotherapy Treatment And Side Effects. More Details



Caring.com

Diet & Fitness Tools

SparkPeople
Get in the competitive spirit and lose weight! SparkPeople is challenging cities across America to get fit and we want Seattle to lead the charge! Go to SparkSeattle.com make it happen! Join Now.
SparkPeople
E-Mail News Alerts
Get breaking news and daily headlines.
Browse all e-mail newsletters
Back To Top