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New Drug Tested For Alzheimer's Disease
POSTED: 3:21 pm PDT April 6,
2005
UPDATED: 3:25 pm PDT April 6,
2005
Alzheimer's Disease robs patients of their memories.Current therapies only slow down the disease, but a new drug in development would not only treat the symptoms; it may actually correct the problem.Married for 59 years, Blanche Wiedenbaum remembers exactly how she met her husband Sy."We lived on the same block, and he used to watch me from his window across the street," she said.
But her memory is failing. She's in the early stages of Alzheimer's Disease."When she's out of the house with other people, they don't know she's got a problem. I think most of them don't realize it," Sy Wiedenbaum said.She takes the medicine Aricept, one of the drugs proven to slow the disease, but she's also in a clinical trial with a new drug called Xaliproden.In Alzheimer's Disease, clumps of an abnormal protein called amyloid build up in the brain cells, and cause them to degenerate and die.Xaliproden prevents that buildup, and may even encourage new brain cells to grow."By blocking the deposition of amyloid within the neurons, and preventing the development of so-called plaques and tangles, we can hopefully keep the patients brain healthy," said Dr. Richard Singer, a Neurologist.Singer is studying the drug. He says though it is not a cure, it does hold a lot of promise."So it's felt by doing this it will prevent not only the worsening of Alzheimer's but it will prevent the development and progression of it as we go along," Singer said.As part of the experiment blanche doesn't know if she is getting the real drug or a placebo.Either way, Sy hopes his wife will be able to hold onto her memories.
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